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SYMPOSIUM: Writing and editing the Ubiquitin code

UPV/EHU Bilbao Avenida Abandoibarra, 3, Bilbao

Post-translational modifications (PTM) by members of the ubiquitin family are at the heart of almost every biological process, including regulation of protein levels, localization, and quality control. Defects in this protein homeostasis (proteostasis) can result in developmental anomalies and disease. An intricate interplay exists among the ubiquitin-family members, with diverse chains and linkages that constitutes a “ubiquitin code”, the full meaning of which is largely…

Training course | CNRS-CIPF | VALENCIA

CIPF- Centro de Investigación Príncipe Felipe C/ Eduardo Primo Yúfera 3, Valencia

Crosstalk between Ub family members under stress conditions 11-15 MARCH 2019 Open blog post

Crosstalk between Ub family members under stress conditions

CIPF- Centro de Investigación Príncipe Felipe C/ Eduardo Primo Yúfera 3, Valencia

UBICODE & UBIRED TRAINING SESSION MARCH 11-15, 2019 CENTRO DE INVESTIGACIÓN PRÍNCIPE FELIPE - VALENCIA, ES In this course we will use tools and technologies to determine the modification of substrates with Ub/UbLs, to learn about their specificity, affinity and their applications.. The capacity to capture and identify distinct chains with these tools will be analysed and compared. Strategies include His6 purification, pan or chain-selective molecular…