1st UBIRED MEETING
Centro de Biología Molecular Severo Ochoa C/ Nicolás Cabrera nº 1; Campus de la Universidad Autónoma de Madrid, Madrid, Madrid, SpainIt will be the first meeting among UBIred integrating groups. The main aim of the meeting is to introduce the Networking Projects and to present the Working Groups. UBIRed CBMSO, 5 de Diciembre de 2018 Ramón Areces Auditorium PROGRAM 10:00-11:15 Rosa Farràs Targeting the Polyamine-Hypusine axis in cáncer José Luis Rosa Regulation of cell proliferation by the ubiquitin ligase HERC1 Gaël Roue Targeting ubiquitin-proteasome system…
Druggability of the Ubiquitin System – which road to take?
CEDOC (Lisbon) - Auditorium Professor Manuel Machado Macedo R. Câmara Pestana 6, Lisboa, PortugalPost-translational modifications (PTM) by members of the Ubiquitin (Ub) family represent an efficient way to regulate almost every biological process. Defects in this homeostatic equilibrium, result in pathologies such as cancer, neurodegeneration, inflammation or multiple infections. For this reason, this research area has become very attractive for fundamental scientists as well as for the pharmaceutical industry aiming to identify potential targets for therapeutic intervention. Our…
SYMPOSIUM: Writing and editing the Ubiquitin code
UPV/EHU Bilbao Avenida Abandoibarra, 3, Bilbao, Bizkaia, SpainPost-translational modifications (PTM) by members of the ubiquitin family are at the heart of almost every biological process, including regulation of protein levels, localization, and quality control. Defects in this protein homeostasis (proteostasis) can result in developmental anomalies and disease. An intricate interplay exists among the ubiquitin-family members, with diverse chains and linkages that constitutes a “ubiquitin code”, the full meaning of which is largely…