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December 2018


December 5, 2018 @ 10:00 am - 5:00 pm
Centro de Biología Molecular Severo Ochoa, C/ Nicolás Cabrera nº 1; Campus de la Universidad Autónoma de Madrid
Madrid, Madrid 28049 Spain
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It will be the first meeting among UBIred integrating groups. The main aim of the meeting is to introduce the Networking Projects and to present the Working Groups. UBIRed CBMSO, 5 de Diciembre de 2018 Ramón Areces Auditorium PROGRAM 10:00-11:15 Rosa Farràs Targeting the Polyamine-Hypusine axis in cáncer José Luis Rosa Regulation of cell proliferation by the ubiquitin ligase HERC1 Gaël Roue Targeting ubiquitin-proteasome system in aggresive B-cell lymphoma 11:15-11:45 Coffee break 11:45-13:00 Emilio Lecona SUMO, ubiquitin and the Dynamics…

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February 2019

Druggability of the Ubiquitin System – which road to take?

February 27
CEDOC (Lisbon) – Auditorium Professor Manuel Machado Macedo, R. Câmara Pestana 6
Lisboa, 1150-078 Portugal
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Post-translational modifications (PTM) by members of the Ubiquitin (Ub) family represent an efficient way to regulate almost every biological process. Defects in this homeostatic equilibrium, result in pathologies such as cancer, neurodegeneration, inflammation or multiple infections. For this reason, this research area has become very attractive for fundamental scientists as well as for the pharmaceutical industry aiming to identify potential targets for therapeutic intervention. Our one-day symposium will therefore focus on the potential developments with regards to the druggability of…

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March 2019

Crosstalk between Ub family members under stress conditions

March 11 - March 15
CIPF- Centro de Investigación Príncipe Felipe, C/ Eduardo Primo Yúfera 3
Valencia, Valencia 46012 Spain
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UBICODE & UBIRED TRAINING SESSION MARCH 11-15, 2019 CENTRO DE INVESTIGACIÓN PRÍNCIPE FELIPE - VALENCIA, ES In this course we will use tools and technologies to determine the modification of substrates with Ub/UbLs, to learn about their specificity, affinity and their applications.. The capacity to capture and identify distinct chains with these tools will be analysed and compared. Strategies include His6 purification, pan or chain-selective molecular traps (to capture ubiquitin, SUMO and NEDD8) and chain specific nanobodies and/or minibodies. TRAINERS Dimitris Xirodimas…

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